Transportation information for Cape Girardeau is provided below. Travel information includes driving directions, maps, airport information and more.
The Cape Girardeau Regional Airport is located approximately 5 miles from downtown Cape Girardeau. The airport is easily accessible via Interstate 55. The airport is mostly used for general aviation but is serviced by American Connection, which is operated by RegionsAir. Other options include Lambert International Airport in St. Louis, which is about a 2-hour drive north, or the Memphis International Airport in Memphis, about a 3-hour drive south.
- 5 miles SW from Cape Girardeau
Map + Directions
Cape Girardeau is located 120 miles southeast of St. Louis and 180 miles north of Memphis. It is accessible via Interstate Highway 55 and U.S. Highway 61. Car rentals are available as a good source of transportation while visiting the area. Car rentals are also available in St. Louis and Memphis, TN for driving to Cape Girardeau if flying into those airports.